Considerable efforts have been made to develop reactive oxygen species (ROS) scavengers for removing high level of ROS. However, most of the reported ROS scavengers are nondegradable and involve harsh reaction conditions as well as utilize various surface ligands. In order to overcome these drawbacks, in the present work, we develop a facile and mild synthesis avenue for preparation of surface-clean hydrogen-doped molybdenum oxide (H_0.34MoO₃) via simply mixing MoO₃ dispersion with aluminum foil under an acidic environment without any surface capping reagents at room temperature. The resulting H_0.34MoO₃ can act as a broad-spectrum ROS scavenger, including ^.OH, H₂O₂, O₂⁻, and ¹O₂ as well as 2, 2-diphenyl-1-picrylhydrazyl (DPPH). The free radical scavenging activity of H_0.34MoO₃ achieves as high as 71.6% and 99.1% for ^.OH and DPPH scavenging, which is comparable and superior to that of ascorbic acid that is a classic free radical scavenger. More significantly, the resulting H_0.34MoO₃ is degrade, which can be degraded into molybdate ions under a neutral environment (pH 7.4).

为了开发用于去除高水平ROS的活性氧（ROS）清除剂，已经做出了相当大的努力。然而，大多数报道的ROS清除剂是不可降解的，并且涉及苛刻的反应条件以及利用各种表面配体。为了克服这些缺点，在目前的工作中，我们开发了一种简单而温和的合成途径，通过在酸性环境下简单地将MoO ₃分散体与铝箔混合即可制备表面清洁的氢掺杂氧化钼（H _0.34 MoO ₃）。在室温下没有任何表面封闭剂。生成的H _0.34 MoO ₃可以用作广谱ROS清除剂，包括^。OH，H ₂Ò ₂，O- ₂ ^- ，和¹ ö ₂以及2，2-二苯基-1-苦基苯肼（DPPH）。H _0.34 MoO _3的自由基清除活性分别达到71.6％和99.1％^。OH和DPPH清除，与经典的自由基清除剂抗坏血酸相比，具有相当的优势。更重要的是，所得的H _0.34 MoO ₃被降解，在中性环境（pH 7.4）下可降解为钼酸根离子。