Super-refractory status epilepticus (SRSE) represents a neurological emergency that is characterized by a lack of response to the third line of antiepileptic treatment, including intravenous general anesthetics. It is a medical challenge with high morbidity and mortality. Electroconvulsive therapy (ECT) has been recommended as a nonpharmacologic option of treatment after other alternatives are unsuccessful. Its effect on the cessation of SRSE has been minimally investigated. The objective of this article is to analyze the effect of ECT on SRSE. For this purpose, a multidisciplinary team created a protocol based on clinical guidelines similar to those described previously by Ray et al. (2017). ECT was applied to six patients with SRSE after the failure of antiepileptic treatment and pharmacologic coma.The objective of each ECT session was to elicit a motor seizure for at least 20 s. SRSE was resolved in all patients after several days of treatment, including ECT as a therapy, without relevant adverse effects. Thus, ECT is an effective and feasible option in the treatment of SRSE, and its place in the algorithm in treatment should be studied due to the uncommon adverse effects and the noninvasive character of the therapy.

中文翻译：

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超难治性癫痫持续状态的电惊厥治疗：具有明确方案的病例系列。

超难治性癫痫持续状态（SRSE）代表一种神经急症，其特征是对第三线抗癫痫治疗（包括静脉全身麻醉药）缺乏反应。这是一个具有高发病率和死亡率的医学挑战。在其他替代方法不成功后，电休克疗法 (ECT) 被推荐作为非药物治疗选择。其对停止 SRSE 的影响的研究很少。本文的目的是分析 ECT 对 SRSE 的影响。为此，一个多学科团队根据类似于 Ray 等人之前描述的临床指南创建了一个方案。（2017）。在抗癫痫治疗失败和药物昏迷后，对 6 名 SRSE 患者应用了 ECT。每次 ECT 疗程的目标是引发至少 20 秒的运动性癫痫发作。经过几天的治疗（包括 ECT 作为治疗）后，所有患者的 SRSE 均得到缓解，且没有相关不良反应。因此，ECT 是治疗 SRSE 的一种有效且可行的选择，由于其不常见的不良反应和非侵入性的特点，应研究其在治疗算法中的地位。