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A fast-responsed fluorescent probe for the selective detection hydrogen sulfide and tert- butoxy radical
Tetrahedron ( IF 2.1 ) Pub Date : 2020-06-04 , DOI: 10.1016/j.tet.2020.131317
Junyang Dong , Jianfeng Hu , Hao Zhang

The fluorescent probe (1) for detecting hydrogen sulfide and tert-butoxy radical in aqueous environment and living cells was first developed. The probe 1 displayed excellent optical properties such as good selectivity, low detection limit (21 nM), quantitative detection (1–10 μM), and very fast response times (<50 s) for monitor of hydrogen sulfide in aqueous environment. Furthermore, the color of the probe 1 solution changed from yellow to colorless when hydrogen sulfide added. More importantly, the probe 1 is successfully used to real-time imaging for hydrogen sulfide and tert-butoxy radical in Hela cells. These merits play a significant role in the process for hydrogen sulfide detection considering the rapid metabolism in organisms.



中文翻译:

快速响应的荧光探针,用于选择性检测硫化氢和叔丁氧基

首先开发了用于在水性环境和活细胞中检测硫化氢和叔丁氧基的荧光探针(1)。探头1具有出色的光学特性,例如选择性好,检测限低(21 nM),定量检测(1-10μM)和非常快的响应时间(<50 s),可用于监测水性环境中的硫化氢。此外,当添加硫化氢时,探针1溶液的颜色从黄色变为无色。更重要的是,探针1已成功用于Hela细胞中硫化氢和叔丁氧基的实时成像。考虑到生物体内的新陈代谢,这些优点在硫化氢检测过程中起着重要作用。

更新日期:2020-06-26
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