Aim

Bioceramic-containing root canal sealers are the most recently introduced sealers in endodontics. The present work reported experiments on a bioceramic-based root canal sealer with the objective of improving its physiochemical properties via reinforcement with each one of the three different nanomaterials: multi-walled carbon nanotubes (MWCNTS), titanium carbide (TC) or boron nitride (BN) in two weight percentages (1 wt% and 2 wt%).

Methodology

Each nanomaterial was added to a definite weight of BioRoot root canal sealer (BioRoot™ RCS, Septodont, Saint-Maur-des-Fossés, France). Three composite groups of each weight percentage were prepared for evaluation: BioRoot/MWCNTS, BioRoot/TC and BioRoot/BN. The initial and final setting times, solubility, elution and pH values of the freshly-mixed and set samples were evaluated and compared to pristine BioRoot™ RCS. Setting times were evaluated using Gilmore needles. Solubility and elution were determined after immersion in water for 24 h. Scanning electron microscopy was used to examine the microstructure of the composite materials.

Results

The 1-wt. % composites possessed significantly shorter initial and final setting times compared with the pristine BioRoot™ RCS (p < 0.05). The 2-wt.% composites exhibited longer initial setting times but significantly shorter final setting times than BioRoot RCS (p < 0.05). Most of the composites had relatively lower solubility and elution profiles, with BioRoot/1-wt.% TC and BioRoot/1-wt.% BN being the lowest (p < 0.05). BioRoot™ RCS and all composites exhibited an alkaline pH profile over a period of 4 weeks and a significantly higher alkaline pH (p < 0.05) was recorded for BioRoot/1-wt.% and Bioroot/2-wt.% TC.

Conclusions

A bioceramic-containing root canal sealer (BioRootTM RCS) with a shorter setting time, an alkaline pH profile, and a relatively lower solubility may be developed by incorporation of nanomaterials.

中文翻译：

---

多壁碳纳米管，碳化钛和氮化硼生物材料增强的基于生物陶瓷的根管封闭剂的理化特性。

目标

含生物陶瓷的根管封闭剂是牙髓学中最新推出的封闭剂。本工作报告了基于生物陶瓷的根管封闭剂的实验，目的是通过增强三种不同纳米材料中的每一种来提高其理化特性：多壁碳纳米管（MWCNTS），碳化钛（TC）或氮化硼（ BN）以两个重量百分比（1 wt％和2 wt％）表示。

方法

将每种纳米材料添加至一定重量的BioRoot根管封闭剂（法国，Saint-Maur-des-Fossé的Septodont，BioRoot™RCS，BioRoot™RCS）。准备了每种重量百分比的三个复合材料组用于评估：BioRoot / MWCNTS，BioRoot / TC和BioRoot / BN。对新鲜混合和凝固的样品的初始和最终凝固时间，溶解度，洗脱和pH值进行了评估，并与原始BioRoot™RCS进行了比较。使用吉尔莫尔针评估凝结时间。在水中浸泡24小时后测定溶解度和洗脱。使用扫描电子显微镜检查复合材料的微观结构。

结果

1-重量。与原始BioRoot™RCS相比，％复合材料的初始和最终凝固时间短得多（p <0.05）。与BioRoot RCS相比，重量百分比为2％的复合材料具有更长的初始凝固时间，但最终凝固时间却明显短（p <0.05）。大多数复合材料的溶解度和洗脱曲线相对较低，其中BioRoot / 1-wt。％TC和BioRoot / 1-wt。％BN最低（p <0.05）。BioRoot™RCS和所有复合材料在4周内均显示出碱性pH值，并且BioRoot / 1-wt。％和Bioroot / 2-wt。％TC的碱性pH值明显更高（p <0.05）。

结论

通过掺入纳米材料，可以开发出具有较短凝固时间，碱性pH值和相对较低溶解度的含生物陶瓷的根管封闭剂（BioRootTM RCS）。