Viral diseases transmitted by mosquitoes, known as arboviruses, pose a significant threat to human life and are a major burden on many health systems around the world. Currently, arbovirus control strategies rely on insecticides or vector source reduction and, in the absence of effective, accessible and affordable vaccines, mainly on symptomatic based, non-specific treatments. However, insecticides have the potential to interfere with non-target organisms, cause environmental toxicity and insecticide resistance reduces their effectiveness as a sustainable control method. Complementary and sustainable strategies are urgently needed. Wolbachia, an invertebrate endosymbiont, has been used as an alternative strategy for arboviral control, through suppression or modification of mosquito populations. Here we discuss the burden that arboviruses impose on human populations and how Wolbachia can be used as a sustainable strategy for control, in alignment with the United Nations- 2030 Agenda for Sustainable Development.

蚊子传播的病毒性疾病，称为虫媒病毒，对人类生命构成重大威胁，并且是全世界许多卫生系统的主要负担。当前，虫媒病毒的控制策略依赖于杀虫剂或载体来源的减少，并且在缺乏有效，容易获得和负担得起的疫苗的情况下，主要依靠基于症状的非特异性治疗。但是，杀虫剂可能会干扰非目标生物，引起环境毒性，而杀虫剂的抗性会降低其作为可持续控制方法的有效性。迫切需要补充和可持续的战略。Wolbachia，一种无脊椎动物内共生体，通过抑制或修饰蚊子种群而被用作控制病毒的替代策略。在这里，我们讨论了虫媒病毒给人类带来的负担，以及如何将沃尔巴克氏菌与联合国《 2030年可持续发展议程》结合起来用作可持续的控制策略。