The high yielding Cu^I-mediated click reaction is an effective procedure for the preparation of oligoporphyrinoid conjugates. However, the Cu^I catalyst leads to the adventitious and usually undesirable insertion of Cu ions into any non-metalated porphyrinoid centers during reaction. Here we report a “sacrificial rotaxane” strategy for the multifunctionalization of porphyrins with free base corroles without incidental copper insertion. This strategy can be considered a general method for implementing Cu^I-mediated click reactions with metal cation sequestration to avoid detrimental effects caused by the presence of copper cations.

中文翻译：

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轮转烷化作为螯合模板，以防止偶然的金属插入复杂的寡色团。

高产率的Cu ^I介导的点击反应是制备寡卟啉类结合物的有效方法。然而，Cu ^I催化剂在反应过程中导致Cu离子不定的，通常不希望的插入Cu离子到任何非金属的卟啉类化合物中心。在这里，我们报告了一种“牺牲性轮烷”策略，用于卟啉与游离碱杂化物的多功能化，而不会偶然插入铜。该策略可以被认为是用于实现Cu ^I介导的点击反应与金属阳离子螯合的常规方法，以避免由于铜阳离子的存在而造成的不利影响。