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Role of pericyte-derived SENP1 in neuronal injury after brain ischemia.
CNS Neuroscience & Therapeutics ( IF 5.5 ) Pub Date : 2020-06-04 , DOI: 10.1111/cns.13398
Meiling Sun 1 , Xiang Chen 1 , Yi-Xuan Yin 2 , Yinping Gao 3 , Li Zhang 4 , Boqian Chen 1 , Yin Ji 5 , Kohji Fukunaga 6 , Feng Han 1 , Ying-Mei Lu 7
Affiliation  

SUMOylation is a posttranslational modification related to multiple human diseases. SUMOylation can be reversed by classes of proteases known as the sentrin/SUMO‐specific proteases (SENPs). In the present study, we investigate the potential role of SENP1 in pericytes in the brain ischemia.

中文翻译:

周细胞衍生的 SENP1 在脑缺血后神经元损伤中的作用。

SUMOylation 是一种与多种人类疾病相关的翻译后修饰。SUMOylation 可以被称为 sentrin/SUMO 特异性蛋白酶 (SENPs) 的蛋白酶类逆转。在本研究中,我们调查了 SENP1 在脑缺血周细胞中的潜在作用。
更新日期:2020-07-17
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