当前位置: X-MOL 学术Muscle Nerve › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Neutralizing BDNF and FGF2 injection into denervated skeletal muscle improve recovery after nerve repair.
Muscle & Nerve ( IF 3.4 ) Pub Date : 2020-06-04 , DOI: 10.1002/mus.26991
Svenja Rink 1 , Christina Chatziparaskeva 2 , Luisa Elles 2 , Stoyan Pavlov 3 , Klaus Nohroudi 2 , Habib Bendella 4 , Levent Sarikcioglu 5 , Marilena Manthou 6 , Sarah Dunlop 7 , Tessa Gordon 8 , Doychin N Angelov 2
Affiliation  

After facial nerve injury and surgical repair in rats, recovery of vibrissal whisking is associated with a high proportion of mono‐innervated neuro‐muscular junctions (NMJs). Our earlier work with Sprague Dawley (SD)/Royal College of Surgeons (RCS) rats, which are blind and spontaneously restore NMJ‐monoinnervation and whisking, showed correlations between functional recovery and increase of fibroblast growth factor‐2 (FGF2) and brain‐derived neurotrophic factor (BDNF) in denervated vibrissal muscles.

中文翻译:

中和BDNF和FGF2注入失神经的骨骼肌可改善神经修复后的恢复。

在大鼠面部神经损伤和外科手术修复后,颤动扫的恢复与单神经神经肌肉接头(NMJs)的比例较高有关。我们早期与Sprague Dawley(SD)/英国皇家外科医学院(RCS)大鼠进行的研究是盲目的并自发地恢复NMJ单神经支配和拂动,显示功能恢复与成纤维细胞生长因子2(FGF2)和脑衍生的颤动性肌肉中的神经源性神经营养因子(BDNF)。
更新日期:2020-06-04
down
wechat
bug