当前位置:
X-MOL 学术
›
Cell Stem Cell
›
论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
There's No I in Team: Cellular Crosstalk Enhances In Vitro Cardiac Maturation.
Cell Stem Cell ( IF 23.9 ) Pub Date : 2020-06-04 , DOI: 10.1016/j.stem.2020.05.009 Richard J Mills 1 , James E Hudson 1
中文翻译:
团队中没有我:细胞串扰可增强体外心脏成熟度。
更新日期:2020-06-04
Cell Stem Cell ( IF 23.9 ) Pub Date : 2020-06-04 , DOI: 10.1016/j.stem.2020.05.009 Richard J Mills 1 , James E Hudson 1
Affiliation
Organoids and microtissues offer the unique opportunity to dissect cell-cell interactions in an organ-specific context without confounding effects of organ failure or organism viability. In a study in this issue of Cell Stem Cell, Giacomelli et al. (2020) add human cardiac fibroblasts into cardiac microtissues and reveal striking fibroblast-endothelial-cardiomyocyte crosstalk that promotes advanced cardiomyocyte maturation.
中文翻译:
团队中没有我:细胞串扰可增强体外心脏成熟度。
类器官和微组织提供了在特定于器官的情况下解剖细胞间相互作用的独特机会,而不会混淆器官衰竭或生物活性的影响。在本期《细胞干细胞》的一项研究中,Giacomelli等人 (2020)将人心脏成纤维细胞添加到心脏微组织中,并揭示了明显的成纤维细胞-内皮-心肌细胞串扰,可促进晚期心肌细胞成熟。