Objective

To measure sodium relaxation times and concentrations in human wrists on a clinical magnetic resonance imaging (MRI) scanner with a density-adapted radial sequence.

Materials and methods

Sodium MRI of human wrists was conducted on a 3T MR system using a dual-tuned ¹H/²³Na surface coil. We performed two studies with 10 volunteers each investigating either sodium T₁ (study 1) or sodium T₂* (study 2) relaxation times in the radiocarpal joint (RCJ) and midcarpal joint (MCJ). Sodium concentrations of both regions were determined.

Results

No differences for transversal of longitudinal relaxation times were found between RCJ and MCJ (T_2,s*(RCJ) = (0.9 ± 0.4) ms; T_2,s*(MCJ) = (0.9 ± 0.3) ms; T_2,l*(RCJ) = (14.9 ± 0.9) ms; T_2,l*(MCJ) = (13.9 ± 1.1) ms; T₁(RCJ) = (19.0 ± 2.4) ms; T₁(MCJ) = (18.5 ± 2.1) ms). Sodium concentrations were (157.7 ± 28.4) mmol/l for study 1 and (159.8 ± 29.1) mmol/l for study 2 in the RCJ, and (172.7 ± 35.6) mmol/l for study 1 and (163.4 ± 26.3) mmol/l for study 2 in the MCJ.

Conclusion

We successfully determined sodium relaxation times and concentrations of the human wrist on a 3T MRI scanner.

中文翻译：

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人类腕关节软骨的钠 MRI：临床 3T MRI 扫描仪的可行性研究。

客观的

在具有密度适应径向序列的临床磁共振成像 (MRI) 扫描仪上测量人类手腕中的钠弛豫时间和浓度。

材料和方法

人类手腕的钠 MRI 是在 3T MR 系统上使用双调谐¹ H/ ²³ Na 表面线圈进行的。我们对 10 名志愿者进行了两项研究，每一项研究调查了桡腕关节 (RCJ) 和中腕关节 (MCJ) 的钠T ₁ (研究 1) 或钠T ₂ * (研究 2) 弛豫时间。测定了两个区域的钠浓度。

结果

RCJ 和 MCJ 的纵向弛豫时间横向没有差异 ( T _2,s *(RCJ) = (0.9 ± 0.4) ms; T _2,s *(MCJ) = (0.9 ± 0.3) ms; T _{2, l} *(RCJ) = (14.9 ± 0.9) ms；T _2,l *(MCJ) = (13.9 ± 1.1) ms；T ₁ (RCJ) = (19.0 ± 2.4) ms；T ₁ (MCJ) = (18.5) ± 2.1) 毫秒)。RCJ 中研究 1 的钠浓度为 (157.7 ± 28.4) mmol/l，研究 2 的钠浓度为 (159.8 ± 29.1) mmol/l，研究 1 的钠浓度为 (172.7 ± 35.6) mmol/l 和 (163.4 ± 26.3) mmol/l l 用于 MCJ 中的研究 2。

结论

我们成功地在 3T MRI 扫描仪上确定了人类手腕的钠弛豫时间和浓度。