Herein environment-friendly solvent 2-propanol-water (95:5 v/v) acidified with 0.5 M oxalic acid was utilized to extract gossypol, a naturally occurring pigment of cottonseed. This polyphenolic pigment gossypol acts as a toxin to cottonseed oil and protein during processing of cottonseed by imparting a dark colouration. The parameters affecting the solvent extraction process, such as temperature, solvent-to-seed ratio, acid concentration and contact time, were studied and optimized along with evaluation of kinetic and thermodynamic parameters. The gossypol extraction followed pseudo-second-order kinetics and the kinetics mechanism displayed the diffusion of gossypol from solid phase to the liquid phase. The extraction process was internal diffusion controlled, and internal solid diffusion was the rate controlling step. The optimum conditions for extraction of gossypol were obtained experimentally as 0.5 M oxalic acid concentration, temperature of 348 K, solvent-to-seed ratio of 15 and an extraction time of 180 min, exhibiting maximum gossypol extraction of 95.43% under these conditions. The activation energy of extraction was found out to be 6.099 kJ/mol while the gossypol extraction process was found out to be endothermic in nature, viable and increased the degree of randomness of extraction process. 2-Propanol-water solvent proved to be a potent green solvent for extraction of gossypol from cottonseed.

在本文中，使用用0.5 M草酸酸化的环保溶剂2-丙醇-水（95：5 v / v）提取棉籽（棉籽的天然色素）。这种多酚颜料棉酚通过赋予深色，在棉籽加工过程中充当棉籽油和蛋白质的毒素。研究并优化了影响溶剂萃取过程的参数，例如温度，溶剂与种子的比例，酸浓度和接触时间，以及动力学和热力学参数的评估。棉酚的提取遵循伪二级动力学，其动力学机理表明棉酚从固相向液相扩散。萃取过程是内部扩散控制的，内部固体扩散是速率控制的步骤。实验获得了棉酚的最佳提取条件：草酸浓度为0.5 M，温度为348 K，溶剂与种子的比例为15，提取时间为180分钟，在这些条件下最大棉酚提取率为95.43％。发现提取的活化能为6.099kJ / mol，而棉酚的提取过程本质上是吸热的，可行并且增加了提取过程的随机性。事实证明，2-丙醇-水溶剂是从棉籽中提取棉酚的有效绿色溶剂。发现提取的活化能为6.099kJ / mol，而棉酚的提取过程本质上是吸热的，可行并且增加了提取过程的随机性。事实证明，2-丙醇-水溶剂是从棉籽中提取棉酚的有效绿色溶剂。发现提取的活化能为6.099kJ / mol，而棉酚的提取过程本质上是吸热的，可行并且增加了提取过程的随机性。事实证明，2-丙醇-水溶剂是从棉籽中提取棉酚的有效绿色溶剂。