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Education in the genomics era: Generating high-quality genome assemblies in university courses.
GigaScience ( IF 9.2 ) Pub Date : 2020-06-03 , DOI: 10.1093/gigascience/giaa058
Stefan Prost 1, 2 , Sven Winter 3, 4 , Jordi De Raad 1, 3 , Raphael T F Coimbra 3, 4 , Magnus Wolf 3, 4 , Maria A Nilsson 1, 4 , Malte Petersen 1 , Deepak K Gupta 1 , Tilman Schell 1 , Fritjof Lammers 1, 3, 4 , Axel Janke 1, 3, 4
Affiliation  

Recent advances in genome sequencing technologies have simplified the generation of genome data and reduced the costs for genome assemblies, even for complex genomes like those of vertebrates. More practically oriented genomic courses can prepare university students for the increasing importance of genomic data used in biological and medical research. Low-cost third-generation sequencing technology, along with publicly available data, can be used to teach students how to process genomic data, assemble full chromosome-level genomes, and publish the results in peer-reviewed journals, or preprint servers. Here we outline experiences gained from 2 master's-level courses and discuss practical considerations for teaching hands-on genome assembly courses.

中文翻译:

基因组学时代的教育:在大学课程中生成高质量的基因组组装。

基因组测序技术的最新进展简化了基因组数据的生成并降低了基因组组装的成本,即使是复杂基因组(如脊椎动物的基因组)也是如此。更实用的基因组课程可以让大学生为生物和医学研究中使用的基因组数据的重要性日益增加做好准备。低成本的第三代测序技术以及公开可用的数据可用于教学生如何处理基因组数据、组装完整的染色体水平基因组,并将结果发表在同行评审期刊或预印本服务器上。在这里,我们概述了从 2 门硕士课程中获得的经验,并讨论了教授动手基因组组装课程的实际考虑因素。
更新日期:2020-06-03
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