Allergic reactions are a rare complication of anaesthesia and anaphylaxis is estimated to affect 1 in every 10,000 anaesthetics in the UK. Investigating reactions can be complex due to the frequent absence of validated skin tests to commonly implicated items, the large number of drugs given during surgery and the presence of non-IgE mediated reactions.

中文翻译：

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确定影响全身麻醉过敏测试结果的因素

过敏反应是一种罕见的麻醉并发症，据估计，在英国，每 10,000 名麻醉剂中就有 1 人受到过敏反应的影响。调查反应可能很复杂，因为通常没有对通常涉及的物品进行经过验证的皮肤测试、手术期间给予的大量药物以及非 IgE 介导的反应的存在。