The present work focused on the assembly of 2-((2-(4-chlorophenylamino)phenylimino)methyl)-6-methoxyphenol as primary ligand (VBL) and bidentate nitrogen donors, namely 2,2′-bipyridyl (L1), 1,10-phenanthroline (L2), and ethylenediamine (L3) as secondary ligands with Cu(II) ion. The synthesized compounds were well characterized by different spectral techniques. From the spectral data, square pyramidal geometry is obtained around Cu(II) center. Compounds so prepared have been subjected to interactions with calf thymus DNA and supercoiled pBR322 plasmid DNA. These studies revealed that these complexes have good interacting property. Anticancer activity to the HeLa (human cervical cancer) and MCF-7 (breast cancer) cell lines showed substantial cytotoxic effect. The compounds were screened for in vitro antibacterial activity, and the results showed that the complexes exhibited good activity against various pathogens.

目前的工作集中在组装作为主要配体（VBL）的2-（（（2-（4-氯苯基氨基）苯基亚氨基）甲基）-6-甲氧基苯酚和二齿氮供体，即2,2'-联吡啶（L1），1 ，10-菲咯啉（L2）和乙二胺（L3）作为具有Cu（II）离子的二级配体。通过不同的光谱技术很好地表征了合成的化合物。从光谱数据中，获得围绕Cu（II）中心的方形金字塔形几何形状。如此制备的化合物已经与小牛胸腺DNA和超螺旋pBR322质粒DNA相互作用。这些研究表明这些络合物具有良好的相互作用性质。对HeLa（人类宫颈癌）和MCF-7（乳腺癌）细胞系的抗癌活性显示出实质性的细胞毒性作用。筛选了这些化合物的体外抗菌活性，结果表明该复合物对各种病原体表现出良好的活性。