Objectives

Research was conducted to study the efficacy of analgesic infiltration treatment in a well-selected population of patients with non-specific drug-resistant chronic low back pain. It studied the pain on a numeric rating scale and the physical and mental condition of patients using a short-form health survey-36, before and six months after invasive pain treatment.

Design

This is a prospective observational single center cohort study.

Setting

The study took place in the Multimodal Pain Therapy Unit of the IRCCS Institute of Neurological Sciences in Bologna, Italy.

Subjects

Four hundred and thirteen out of a total 538 patients admitted to the unit with non-specific drug-resistant chronic low back pain were enrolled in the study.

Method

Patients were enrolled with written consent between April 2017 and November 2018. The study assessed NRS, BDI and SF-36 scores before and six months after mini-invasive treatment.

Results

There is an inverse correlation between Mental Component Scale (MCS) and Physical component scale as measured by SF-36. Older patients in a worse physical condition but with a more positive outlook on their quality of life were more likely to improve after invasive treatment (p < 0.001). The BDI scale is more effective in the diagnosis of depression than MCS.

Conclusions

The prognostic value of MCS given to the patient before mini-invasive treatment could lead physicians to adopt a multimodal approach that includes consideration of the psychological features of pain and possibly antidepressant therapy.

中文翻译：

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接受微创治疗的非特异性慢性腰痛患者预后因素的黄旗：一项队列研究。

目标

进行了研究以研究镇痛渗透治疗在精心挑选的非特异性耐药慢性腰痛患者人群中的疗效。它在侵入性疼痛治疗前和治疗后 6 个月，使用简短的健康调查 36 研究了数字评分量表上的疼痛以及患者的身心状况。

设计

这是一项前瞻性观察性单中心队列研究。

设置

该研究在意大利博洛尼亚 IRCCS 神经科学研究所的多模式疼痛治疗部门进行。

科目

入住该病房的 538 名患有非特异性耐药慢性腰痛的患者中有 413 名参加了该研究。

方法

患者在 2017 年 4 月至 2018 年 11 月期间获得书面同意。该研究评估了微创治疗前后的 NRS、BDI 和 SF-36 评分。

结果

SF-36 测量的心理成分量表 (MCS) 和身体成分量表之间存在负相关。身体状况较差但对生活质量持更积极态度的老年患者在侵入性治疗后更有可能改善（p  < 0.001）。BDI 量表在诊断抑郁症方面比 MCS 更有效。

结论

在微创治疗之前给予患者 MCS 的预后价值可能会导致医生采用多模式方法，包括考虑疼痛的心理特征和可能的抗抑郁治疗。