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A Sesquiterpene Lactone from Irpex lacteus
Chemistry of Natural Compounds ( IF 0.8 ) Pub Date : 2020-05-01 , DOI: 10.1007/s10600-020-03047-6
Jian-Hai Ding , Zheng-Hui Li , Tao Feng , Ji-Kai Liu

A new tremulane sesquiterpene lactone, named irlactin K (1), was isolated from the culture broth of the basidiomycete Irpex lacteus. The structure of the new compound was established through extensive spectroscopic analyses. The compound was tested for its cytotoxicity against five human cancer cell lines and for its inhibitory activity against isozymes of 11β-hydroxysteroid dehydrogenases.

中文翻译:

来自 Irpex lacteus 的倍半萜内酯

从担子菌 Irpex 乳杆菌的培养液中分离出一种新的颤音倍半萜内酯,名为 irlactin K (1)。新化合物的结构是通过广泛的光谱分析确定的。测试了该化合物对五种人类癌细胞系的细胞毒性和对 11β-羟基类固醇脱氢酶同工酶的抑制活性。
更新日期:2020-05-01
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