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Evaluations of biosynthesized Ag nanoparticles via Allium Sativum flower extract in biological applications
Applied Nanoscience ( IF 3.869 ) Pub Date : 2020-06-03 , DOI: 10.1007/s13204-020-01463-2
K. Velsankar , R. Preethi , P.S. Jeevan Ram , M. Ramesh , S. Sudhahar

The eco-friendly phytomediated synthesis of Ag nanoparticles provides better efficient applications than synthetic methods. Ag nanoparticles are considered by researchers due to its specific properties. The phytochemical analysis of Allium Sativum flower extract provides the phytochemicals exist in it. Due to this, the efficient eco-friendly synthesis of Ag nanoparticles via Allium Sativum flower extract has performed. The X-ray diffraction pattern exposes the crystalline nature with the mean crystallite size at 25 nm. The Fourier Transform Infra-Red spectrum displays the phytochemicals involved in the synthesis. The UV–Visible spectrum illustrates the formation of Ag nanoparticles with SPR band at 436 nm. The particle size analyzer demonstrates the size of formed Ag particles in 20–35 nm. The morphological, elemental and structural analyzes demonstrate the formation of spherical shaped Ag nanoparticles. The formation of Ag nanoparticles was confirmed by the appearance of Ag peak in Energy Dispersive X-ray Diffraction spectrum and mapping study. The antimicrobial activity explains the effective antimicrobial effect on human pathogens. The antioxidant activity reports the efficient scavenging property of synthesized Ag nanoparticles. The anti-inflammatory activity reveals the potential ability of protein denaturation on bovine serum albumin. The anti-diabetic activity exhibits much inhibition on α-Amylase. The anticancer activity reports the effective inhibition of synthesized Ag nanoparticles on human MCF-7 breast cancer cells.



中文翻译:

大蒜花提取物生物合成银纳米颗粒的生物应用评价

银纳米颗粒的生态友好的植物介导合成提供了比合成方法更好的有效应用。Ag纳米颗粒由于其特殊的性能而被研究人员考虑。大蒜花提取物的植物化学分析提供了其中存在的植物化学物质。因此,通过大蒜素有效高效地合成了银纳米颗粒花提取物已执行。X射线衍射图显示出晶体性质,其平均微晶尺寸为25nm。傅立叶变换红外光谱显示了合成中涉及的植物化学成分。紫外可见光谱说明了具有436 nm SPR谱带的银纳米颗粒的形成。粒度分析仪可显示20-35 nm处形成的Ag颗粒的大小。形态,元素和结构分析表明球形Ag纳米颗粒的形成。通过在能量色散X射线衍射谱中的Ag峰的出现和作图研究证实了Ag纳米颗粒的形成。抗菌活性说明了对人类病原体的有效抗菌作用。抗氧化剂活性报告了合成的银纳米颗粒的有效清除性能。牛血清白蛋白。抗糖尿病活性对α-淀粉酶表现出很大的抑制作用。该抗癌活性报告了合成的Ag纳米粒子对人MCF-7乳腺癌细胞的有效抑制作用。

更新日期:2020-06-03
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