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Splenic Complications of Babesia microti Infection in Humans: A Systematic Review.
Canadian Journal of Infectious Diseases and Medical Microbiology ( IF 2.8 ) Pub Date : 2020-05-28 , DOI: 10.1155/2020/6934149
Igor Dumic 1, 2 , Cristian Madrid 2 , Libardo Rueda Prada 2 , Charles W Nordstrom 1, 2 , Pahnwat Tonya Taweesedt 3 , Poornima Ramanan 4
Affiliation  

Splenic complications of acute Babesia microti infection include splenomegaly, splenic infarct, and splenic rupture. These complications are relatively rarely reported, and the aim of this research was to synthetize data on this topic according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines using the PubMed database. In this review, we find that unlike other severe complications of babesiosis, splenic infarct and rupture occur in younger and immunocompetent patients, and they do not correlate with parasitemia level. Furthermore, admission hemoglobin of 10 mg/dl or less, platelet count of 50 × 10⁹/L or less, presence of hemodynamic instability, and splenic rupture were associated independently with an increased risk of requiring splenectomy. As babesiosis is an emerging tick-borne zoonosis, we hope that this review will help to raise awareness among clinicians regarding this rare but potentially life-threatening complication.

中文翻译:

人类小肠杆状菌感染的脾脏并发症:系统评价。

急性小be虫的脾脏并发症感染包括脾肿大,脾梗塞和脾破裂。这些并发症的报道相对很少,本研究的目的是使用PubMed数据库根据系统评价和荟萃分析的首选报告项目(PRISMA)指南,综合该主题的数据。在这篇综述中,我们发现,与其他严重的巴贝西斯病并发症不同,年轻且具有免疫功能的患者发生脾梗塞和破裂,并且与寄生虫血症水平无关。此外,入院血红蛋白为10 mg / dl或以下,血小板计数为50×10⁹/ L或以下,血流动力学不稳定和脾破裂均与需要行脾切除术的风险增加相关。由于巴贝虫病是新兴的壁虱传播的人畜共患病,
更新日期:2020-05-28
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