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coronapp: a Web Application to Annotate and Monitor SARS-CoV-2 Mutations
bioRxiv - Bioinformatics Pub Date : 2020-09-10 , DOI: 10.1101/2020.05.31.124966
Daniele Mercatelli , Luca Triboli , Eleonora Fornasari , Forest Ray , Federico M. Giorgi

The avalanche of genomic data generated from the SARS-CoV-2 virus requires the development of tools to detect and monitor its mutations across the world. Here, we present a webtool, coronapp, dedicated to easily processing user-provided SARS-CoV-2 genomic sequences and visualizing current worldwide status of SARS-CoV-2 mutations. The webtool allows users to highlight mutations and categorize them by frequency, country, genomic location and effect on protein sequences, and to monitor their presence in the population over time. The tool is available at http://giorgilab.unibo.it/coronapp/ for the worldwide dataset and at http://giorgilab.unibo.it/coronannotator/ for the annotation of user-provided sequences. The full code is freely shared at https://github.com/federicogiorgi/giorgilab/tree/master/coronapp

中文翻译:

coronapp:用于注释和监视SARS-CoV-2突变的Web应用程序

从SARS-CoV-2病毒生成的大量基因组数据需要开发工具来检测和监视全世界的突变。在这里,我们介绍了一个web工具,coronapp,致力于轻松处理用户提供的SARS-CoV-2基因组序列,并可视化SARS-CoV-2突变的全球现状。该网络工具允许用户突出显示突变并按频率,国家,基因组位置和对蛋白质序列的影响对其进行分类,并随时间监视其在群体中的存在。该工具可在http://giorgilab.unibo.it/coronapp/上获取全球数据集,在http://giorgilab.unibo.it/coronannotator/上可以获取用户提供的序列。完整代码可在https://github.com/federicogiorgi/giorgilab/tree/master/coronapp中免费共享
更新日期:2020-09-11
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