Abstract

We aimed to investigate associations of dietary intakes with unhealthy metabolic phenotype development, in normal weight and overweight/obese adults separately. A total of 1114 individuals, aged ≥19 years, with healthy phenotype in the third examination cycle of Tehran Lipid and Glucose Study were followed until the fifth examination. Dietary intakes were estimated using the food frequency questionnaires, collected during the study. The participants were grouped as normal weight and overweight/obese according to the baseline body mass index (BMI). Unhealthy metabolic status was determined as having more than one component of metabolic syndrome using the Joint Interim Statement. Regardless of BMI, higher intakes of magnesium, dairy products, poultry, apples/pears, citrus fruits, and tea/coffee decreased the risk of developing unhealthy phenotype, while higher intakes of fast foods, organ meats, and potatoes increased the risk. Food intake can influence the transition to unhealthy phenotype in metabolically healthy adults, irrespective of the BMI status.

摘要

我们的目标是分别调查正常体重和超重/肥胖成年人的饮食摄入与不良健康代谢表型发展的关系。在德黑兰血脂和葡萄糖研究的第三个检查周期中，共有1114名年龄≥19岁且具有健康表型的个体被随访至第五次检查。使用研究期间收集的食物频率调查表估算饮食摄入量。根据基线体重指数（BMI）将参与者分为正常体重和超重/肥胖。使用《联合临时声明》确定不健康的代谢状态为代谢综合征的一种以上成分。无论BMI如何，较高的镁，奶制品，家禽，苹果/豌豆，柑橘类水果和茶/咖啡的摄入量都可以降低产生不健康表型的风险，而摄入更多快餐，内脏肉和土豆则增加了患病风险。无论BMI状况如何，食物摄入都会影响代谢健康成人向不健康表型的转变。