Novel antimicrobial drugs are urgently needed to counteract the increasing occurrence of
bacterial resistance. Extracts of Cannabis sativa have been used for the treatment of several diseases
since ancient times. However, its phytocannabinoid constituents are predominantly associated with
psychotropic effects and medical applications far beyond the treatment of infections. It has been
demonstrated that several cannabinoids show potent antimicrobial activity against primarily Grampositive
bacteria including methicillin‐resistant Staphylococcus aureus (MRSA). As first in vivo
efficacy has been demonstrated recently, it is time to discuss whether cannabinoids are promising
antimicrobial drug candidates or overhyped intoxicants with benefits.




中文翻译：

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大麻素是有前途的抗菌药物还是有好处的麻醉剂？

迫切需要新型抗菌药物来应对日益增加的
细菌耐药性。
自古以来，大麻提取物就被用于治疗多种疾病。然而，其植物大麻素成分主要与
精神作用和远远超出感染治疗范围的医疗应用有关。已经证明，几种大麻素对主要的革兰氏阳性细菌（包括耐甲氧西林金黄色葡萄球菌（MRSA））
表现出有效的抗菌活性。
随着最近首次证明体内
功效，现在是时候讨论大麻素是否是有前途的
抗菌药物候选者或被过度炒作的具有益处的麻醉剂。