Itaconate is an immunometabolite with anti-inflammatory and anti-microbial properties. Riquelme et al. (2020) demonstrate that pathogenic Pseudomonas aeruginosa drives itaconate production by macrophages, which it then uses as a carbon source for biofilm formation, allowing it to persist during infection and suppress inflammation.

中文翻译：

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假单胞菌通过吃掉衣康酸酯而持久。

衣康酸酯是具有抗炎和抗微生物特性的免疫代谢物。Riquelme等。（2020）证明，致病性铜绿假单胞菌通过巨噬细胞驱动衣康酸的产生，然后将其用作生物膜形成的碳源，使其在感染期间持续存在并抑制炎症。