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Determination of the Microstructure of Decellularized Dermal Scaffolds
Nanotechnologies in Russia Pub Date : 2020-04-13 , DOI: 10.1134/s1995078019040074
R. A. Kamyshinsky , K. G. Antipova , E. V. Kuevda , D. M. Kuznetsova , T. D. Patsaev , E. S. Morokov , E. A. Khramtsova , D. Ya. Aleinik , M. N. Egorikhina , T. E. Grigoryev , E. A. Gubareva , A. L. Vasiliev

One of the most important aspects of regenerative medicine is the selection of the scaffold—the biological skeleton of the tissue-engineering structure. To reproduce the structure and properties of damaged tissue and maintain the cell adhesion and proliferation, it is optimal to use scafflds obtained by decellularization of native organs with subsequent recellularization of various cell lines. Using the methods of environmental scanning electron microscopy and scanning pulsed ultrasound microscopy, the microstructure of native and decellularized matrixes of dermal tissues was determined.

中文翻译:

脱细胞真皮支架的微观结构测定

再生医学最重要的方面之一是支架的选择-组织工程结构的生物骨架。为了再现受损组织的结构和特性并维持细胞粘附和增殖,最理想的方法是使用通过自然器官脱细胞并随后对各种细胞系进行重新细胞化而获得的支架。使用环境扫描电子显微镜和扫描脉冲超声显微镜的方法,确定了真皮组织的天然和脱细胞基质的微观结构。
更新日期:2020-04-13
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