Abstract

New N-derivatives of daunorubicin are obtained using aromatic aldehydes by one-step reductive amination. The obtained compounds are found to exhibit a high cytotoxic activity.

中文翻译：

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一步还原胺化合成柔红霉素ubi衍生物

摘要

使用芳族醛类通过一步还原胺化获得新的柔红霉素N衍生物。发现获得的化合物表现出高的细胞毒性活性。