The process of the DNA sequencing in solid-state nanopores is considered. The theoretical modeling of ionic, thermionic, and tunnel currents for nanopores with the gold electrodes located in bio-liquids has been carried out. It is shown that both the ionic and thermionic currents are several orders of magnitude weaker than the direct tunneling current, which reaches several hundred of nA. The differences between the values of direct tunnel currents for four DNA nucleotides, as well as for guanine-cytosine and thymine-adenine nucleotide pairs are significant, which makes it easy to identify each DNA nucleotide. The behavior of the differential quantum conductance of the corresponding molecular junctions is also analyzed. The histograms for tunnel currents and conductance for four the DNA and guanine-cytosine and thymine-adenine nucleotides are plotted.

考虑了固态纳米孔中DNA测序的过程。对金孔位于生物液体中的纳米孔的离子，热离子和隧道电流进行了理论建模。结果表明，离子电流和热离子电流都比直接隧穿电流弱了几个数量级，后者达到数百nA。四个DNA核苷酸以及鸟嘌呤-胞嘧啶和胸腺嘧啶-腺嘌呤核苷酸对的直接隧道电流值之间的差异非常大，这使识别每个DNA核苷酸变得容易。还分析了相应分子结的差分量子电导的行为。