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Chemisorption of Glycidyl Spacer on Magnetic Nanoparticles and Immobilization of Albumin and Quinacrine
Russian Journal of General Chemistry ( IF 0.9 ) Pub Date : 2020-06-04 , DOI: 10.1134/s1070363220030111
D. V. Korolev , V. N. Postnov , T. N. Romanova , V. N. Zorin , G. A. Shulmeyster , E. B. Naumysheva , N. V. Evreinova , I. V. Murin

Abstract

Chemisorption of a glycidyl spacer on the surface of magnetic nanoparticles from three solvents has been performed. It has been shown that the chemisorption from benzene is the most efficient. Human albumin and quinacrine as a model pharmaceutical have been immobilized via a glycidyl spacer. A mechanism of the interaction of albumin and quinacrine with glycidyl groups has been suggested.


中文翻译:

缩水甘油基间隔物在磁性纳米粒子上的化学吸附及白蛋白和奎那克林的固定化

摘要

已经进行了三种溶剂对磁性纳米颗粒表面的缩水甘油基间隔物的化学吸附。已经表明,从苯的化学吸附是最有效的。已经通过缩水甘油基间隔物固定了人白蛋白和奎纳克林作为模型药物。已经提出了白蛋白和奎纳克林与缩水甘油基相互作用的机理。
更新日期:2020-06-04
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