Abstract Adipose tissue reconstruction is an important technique for soft tissue defects caused by facial plastic surgery and trauma. Adipose tissue reconstruction can be repaired by fat transplantation and biomaterial filling, but there are some problems in fat transplantation, such as second operation and limited resources. The application of advanced artificial biomaterials is a promising strategy. In this paper, injectable biomaterials and three-dimensional (3D) tissue-engineered scaffold materials for adipose tissue reconstruction in plastic surgery are reviewed. Injectable biomaterials include natural biomaterials and artificial biomaterials, which generally have problems such as high absorptivity of fillers, repeated injection, and rejection. In recent years, the technology of new 3D tissue-engineering scaffold materials with adipose-derived stem cells (ADSCs) and porous scaffold as the core has made good progress in fat reconstruction, which is expected to solve the current problem of clinical adipose tissue reconstruction, and various biomaterials preparation technology and transformation research also provide the basis for clinical transformation of fat tissue reconstruction.

中文翻译：

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整形外科脂肪组织重建生物材料研究进展

摘要 脂肪组织重建是修复面部整形手术和外伤引起的软组织缺损的一项重要技术。脂肪组织重建可以通过脂肪移植和生物材料填充修复，但脂肪移植存在二次手术、资源有限等问题。先进人工生物材料的应用是一个很有前景的策略。本文综述了用于整形外科脂肪组织重建的可注射生物材料和三维 (3D) 组织工程支架材料。可注射生物材料包括天然生物材料和人工生物材料，它们普遍存在填充剂吸收率高、重复注射、排斥反应等问题。最近几年，