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Evaluating hydrodynamics in a bioreactor with liquid phase dispersion in the gas phase
International Journal of Chemical Reactor Engineering ( IF 1.6 ) Pub Date : 2020-04-22 , DOI: 10.1515/ijcre-2019-0131
Arash Arabmarkadeh 1 , Mohsen Nosrati 1 , Mohammad Amin Hejazi 2 , Seyed Mohammad Mousavi 1
Affiliation  

Abstract Bioreactors are used in many biochemical industries to produce commercial life products such as medicines, enzymes, perfumes, paints and antibiotics. In the presented study, a specially shaped bioreactor has been designed, built and operated to increase the mass transfer coefficient. The constructed bioreactor, according to type of microorganisms, can provide high amounts of oxygen or carbon dioxide. Moreover, the manuscript was aimed at investigating the hydrodynamic properties of the bioreactor. The bioreactor was constructed from three parts including shower in upper part, middle section for mass transfer and bottom section as a reservoir. Liquid flow rate, shower holes diameter, aeration velocity and the middle part height of the bioreactor have been studied as factors influencing the hydrodynamics. The results showed that the highest mass transfer coefficient was 30.1 1/h which was achieved when the liquid flow rate, the shower holes diameter, aeration velocity and middle part height of the bioreactor were 280 mL/min, 2 mm, 0.03 vvm and 60 cm, respectively.

中文翻译:

评估具有液相分散在气相中的生物反应器中的流体动力学

摘要 生物反应器在许多生化工业中用于生产商业生活产品,如药物、酶、香水、油漆和抗生素。在本研究中,设计、建造和运行了一个特殊形状的生物反应器,以增加传质系数。根据微生物的类型,构建的生物反应器可以提供大量的氧气或二氧化碳。此外,手稿旨在研究生物反应器的流体动力学特性。生物反应器由三部分构成,包括上部的淋浴器、用于传质的中间部分和作为储存器的底部部分。液体流速、喷淋孔直径、曝气速度和生物反应器的中间部分高度已作为影响流体动力学的因素进行了研究。
更新日期:2020-04-22
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