High-strength macroporous monoliths can be obtained by simply mixing boehmite nanofiber aqueous acetate dispersions with methyltrimethoxysilane. On the boehmite nanofiber-polymethylsilsesquioxane monoliths, we can fabricate structures smaller than a millimeter in size by computer numerical control (CNC) milling, resulting in a machined surface that is superhydrophobic and biocompatible. Using this strategy, we fabricated a superhydrophobic multiwell plate which holds water droplets to produce 3D cell culture environments for various cell types. We expect these superhydrophobic monoliths to have future applications in 3D tissue construction.

中文翻译：

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CNC铣削的超疏水大孔整料，用于3D细胞培养

通过简单地将勃姆石纳米纤维乙酸盐水性分散体与甲基三甲氧基硅烷混合，可以获得高强度大孔整料。在勃姆石纳米纤维-聚甲基倍半硅氧烷整料上，我们可以通过计算机数控（CNC）铣削来制造尺寸小于1毫米的结构，从而形成具有超疏水性和生物相容性的机械加工表面。使用这种策略，我们制造了一种超疏水多孔板，该多孔板可容纳水滴以产生适用于各种细胞类型的3D细胞培养环境。我们希望这些超疏水整体材料在3D组织构造中具有未来的应用。