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Tobramycin Serum Concentrations in Tracheostomy-Dependent Children Receiving Inhaled Tobramycin
Pediatric Allergy, Immunology, and Pulmonology ( IF 0.9 ) Pub Date : 2020-06-17 , DOI: 10.1089/ped.2020.1161 Kaitlin M Hughes 1 , A Ioana Cristea 2 , Emma M Tillman 3
Pediatric Allergy, Immunology, and Pulmonology ( IF 0.9 ) Pub Date : 2020-06-17 , DOI: 10.1089/ped.2020.1161 Kaitlin M Hughes 1 , A Ioana Cristea 2 , Emma M Tillman 3
Affiliation
Introduction: In recent years, administration of inhaled aminoglycosides has gained popularity in tracheostomy-dependent pediatric patients because of medication delivery to the target site of action while minimizing systemic absorption and adverse effects. A recent report of detectable serum tobramycin concentrations in critically ill children receiving inhaled tobramycin 300 mg every 12 h prompted our investigation in tracheostomy-dependent pediatric patients receiving inhaled tobramycin 80 mg every 8 h.
中文翻译:
接受吸入妥布霉素的依赖气管切开术的儿童的妥布霉素血清浓度
简介:近年来,吸入性氨基糖苷类药物在依赖气管切开术的儿科患者中越来越受欢迎,因为它可以将药物输送到目标作用部位,同时最大限度地减少全身吸收和不良反应。最近有报道称,重症儿童每 12 小时吸入 300 毫克妥布霉素可检测到血清妥布霉素浓度,这促使我们对每 8 小时吸入 80 毫克妥布霉素的气管切开依赖性儿科患者进行调查。
更新日期:2020-06-22
中文翻译:
接受吸入妥布霉素的依赖气管切开术的儿童的妥布霉素血清浓度
简介:近年来,吸入性氨基糖苷类药物在依赖气管切开术的儿科患者中越来越受欢迎,因为它可以将药物输送到目标作用部位,同时最大限度地减少全身吸收和不良反应。最近有报道称,重症儿童每 12 小时吸入 300 毫克妥布霉素可检测到血清妥布霉素浓度,这促使我们对每 8 小时吸入 80 毫克妥布霉素的气管切开依赖性儿科患者进行调查。