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Combined Molecular and Phenotypic Antimicrobial Susceptibility Testing Is Beneficial in Detection of ESBL and AmpC Beta-Lactamase Producing Isolates of Enterobacteriaceae in Pediatric Patients with Bloodstream Infections.
Microbial Drug Resistance ( IF 2.6 ) Pub Date : 2020-07-07 , DOI: 10.1089/mdr.2019.0432
Eleanor A Powell 1, 2 , Nadim Khalil 3 , Barbara DeBurger 1 , Joel E Mortensen 1, 2
Affiliation  

Objectives: The aim was to assess the potential advantage of combined genotypic testing with phenotypic antimicrobial susceptibility testing (AST) to detect AmpC β-lactamases (AmpC) and extended-spectrum β-lactamases (ESBL) producing Enterobacteriaceae isolated from blood cultures in a pediatric population.

中文翻译:

结合分子和表型的药敏试验对检测有血流感染的小儿肠杆菌科细菌产生ESBL和AmpCβ-内酰胺酶分离株是有益的。

目的:目的是评估将基因型测试与表型抗菌药性测试(AST)结合起来检测从儿科血液培养物中分离出的产肠杆菌科细菌的AmpCβ-内酰胺酶(AmpC)和超广谱β-内酰胺酶(ESBL)的潜在优势。人口。
更新日期:2020-07-10
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