A new external oxidant-free electrochemical dehydrogenative cross-coupling of xanthenes and ketones for the preparation of functionalized 9-alkyl-9H-xanthenes was developed. This method enables the formation of a new C(sp³)–C(sp³) bond through release of H₂ as the major byproduct at room temperature, and features mild conditions, high atom economy, excellent functional-group tolerance, scalability and facile applications in pharmaceutical chemistry.

中文翻译：

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黄嘌呤与酮的电化学脱氢交叉偶联。

开发了一种新的无氧黄酮和酮的无外部氧化剂的电化学脱氢交联反应，用于制备功能化的9-烷基-9 H-黄嘌呤。该方法能够通过在室温下释放H ₂作为主要副产物而形成新的C（sp ³）–C（sp ³）键，并且具有温和的条件，高原子经济性，出色的官能团耐受性，可扩展性和在药物化学中的简便应用。