Monitoring regional pulmonary ventilation and pulsatile perfusion changes in a 3D region of interest (ROI) of the lung is a promising application for electrical impedance tomogra-phy (EIT). This paper describes a 3D analytical reconstruction algorithm that was embed-ded in a prototype EIT system to enable a real-time image reconstruction at nearly 20 frames per second for monitoring impedance changes in the chest in real-time. The deriva-tion and results of the 3D analytical forward solution and inverse solution and details of the real-time reconstruction algorithm are given. The algorithm and EIT system are validat-ed with simulated data, in-vitro phantoms, and finally shown to be capable of imaging ventilation and pulsatile perfusion in human subjects. The human subject data was ob-tained using a high-precision, high-speed and simultaneous multiple current source (SMS-EIT) developed by GE Research. Data was collected using four rows of 8 electrodes for a healthy adult male subject and 2 rows of 16 electrodes for six healthy human female sub-jects, with one row placed above the breasts and a second row placed at the infra-mammary fold. Each of the female subjects performed a breathing maneuver with a volumetric incen-tive spirometer, and the volume of air inhaled was calculated from the EIT images. Pulsa-tile perfusion images were computed from this data, and regional lung filling was also analyzed.

中文翻译：

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用于肺功能监测的实时同时多源EIT实时成像的3D重建算法

监测肺部3D感兴趣区域（ROI）中的区域肺通气和搏动性灌注变化是电阻抗断层扫描（EIT）的有希望的应用。本文介绍了一种3D分析重建算法，该算法嵌入到EIT原型系统中，能够以每秒近20帧的速度进行实时图像重建，以实时监控胸部的阻抗变化。给出了3D解析正解和反解的推导和结果以及实时重建算法的细节。该算法和EIT系统已通过仿真数据，体外体模进行了验证，并最终证明能够对人类受试者的通气和搏动性灌注进行成像。人类受试者的数据是使用高精度获得的，GE Research开发的高速并发多路电流源（SMS-EIT）。对于健康的成年男性受试者，使用四行8电极的电极，对于六个健康的人类女性受试者使用2行的16电极的电极，其中第一行放置在乳房上方，第二行放置在乳房下折叠处。每个女性受试者使用容积式肺活量计进行呼吸动作，并从EIT图像计算吸入的空气量。从该数据计算出脉搏灌注图像，并分析了局部肺充盈。一排放在乳房上方，第二排放在乳房下折叠处。每个女性受试者使用容积式肺活量计进行呼吸动作，并从EIT图像计算吸入的空气量。从该数据计算出脉搏灌注图像，并分析了局部肺充盈。一排放在乳房上方，第二排放在乳房下折叠处。每个女性受试者使用容积式肺活量计进行呼吸动作，并从EIT图像计算吸入的空气量。从该数据计算出脉搏灌注图像，并分析了局部肺充盈。