Increased reactive oxygen species (ROS) generation may disrupt the oocytes function and their competence. In this study, we introduced BTZO‐1, a new supplement that can regulate the oxidative stress. Addition of BTZO‐1 during IVM of bovine oocytes improved their developmental competence in the term of improvement of blastocyst rates. In addition, the quality of the produced embryos was improved by decreasing the apoptosis level by showing a decreased number of TUNNEL positive cells.

中文翻译：

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抗氧化反应元件激活剂BTZO-1可提高牛卵母细胞的发育能力

活性氧（ROS）生成增加可能会破坏卵母细胞的功能及其能力。在这项研究中，我们介绍了BTZO-1，这是一种可以调节氧化应激的新补品。牛卵母细胞IVM期间添加BTZO-1在提高胚泡率方面改善了它们的发育能力。另外，通过显示出减少的TUNNEL阳性细胞数量来降低细胞凋亡水平，从而提高了所产生胚胎的质量。