Environmental and human health challenges are pronounced in Asia, an exceptionally diverse and complex region where influences of global megatrends are extensive and numerous stresses to environmental quality exist. Identifying priorities necessary to engage grand challenges can be facilitated through horizon scanning exercises, and to this end we identified and examined 23 priority research questions needed to advance toward more sustainable environmental quality in Asia, as part of the Global Horizon Scanning Project. Advances in environmental toxicology, environmental chemistry, biological monitoring, and risk‐assessment methodologies are necessary to address the adverse impacts of environmental stressors on ecosystem services and biodiversity, with Asia being home to numerous biodiversity hotspots. Intersections of the food–energy–water nexus are profound in Asia; innovative and aggressive technologies are necessary to provide clean water, ensure food safety, and stimulate energy efficiency, while improving ecological integrity and addressing legacy and emerging threats to public health and the environment, particularly with increased aquaculture production. Asia is the largest chemical‐producing continent globally. Accordingly, sustainable and green chemistry and engineering present decided opportunities to stimulate innovation and realize a number of the United Nations Sustainable Development Goals. Engaging the priority research questions identified herein will require transdisciplinary coordination through existing and nontraditional partnerships within and among countries and sectors. Answering these questions will not be easy but is necessary to achieve more sustainable environmental quality in Asia. Environ Toxicol Chem 2020;39:1485–1505. © 2020 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.

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追求可持续的环境质量：亚洲的优先研究问题。

亚洲是一个极为多样化和复杂的地区，在这个地区，人类面临着巨大的环境和人类健康挑战，全球大趋势的影响广泛，并且对环境质量的压力也很大。可以通过地平线扫描练习来确定应对重大挑战所必需的优先级，为此，我们确定并研究了23个优先研究问题，这些问题是全球地平线扫描项目的一部分，旨在提高亚洲的可持续环境质量。为了解决环境压力因素对生态系统服务和生物多样性的不利影响，必须有环境毒理学，环境化学，生物监测和风险评估方法方面的进步，而亚洲是众多生物多样性热点地区。在亚洲，食物，能源，水之间的联系十分广泛。创新和积极的技术对于提供清洁水，确保食品安全和提高能源效率是必要的，同时还可以改善生态完整性并解决对公共健康和环境的遗留和新出现的威胁，特别是随着水产养殖产量的增加。亚洲是全球最大的化学生产大洲。因此，可持续和绿色化学与工程为刺激创新和实现许多联合国可持续发展目标提供了确定的机会。参与本文确定的优先研究问题，将需要通过国家和部门之间以及国家和部门之间现有的和非传统的伙伴关系进行跨学科的协调。2020年《环境毒理学》； 39：1485–1505。©2020作者。Wiley Periodicals LLC代表SETAC发布的《环境毒理学和化学》。