Melatonin In Acute Mania Investigation (MIAMI‐UK). A randomized controlled trial of add‐on melatonin in bipolar disorder,Bipolar Disorders

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Melatonin In Acute Mania Investigation (MIAMI‐UK). A randomized controlled trial of add‐on melatonin in bipolar disorder
Bipolar Disorders ( IF 5.4 ) Pub Date : 2020-05-31 , DOI: 10.1111/bdi.12944
Digby J Quested _{1,

2} , Jessica C Gibson ₁ , Ann L Sharpley ₂ , Julia H Cordey ₁ , Alexis Economou _{1,

3} , Franco De Crescenzo _{1,

2,

4,

5} , Merryn Voysey ₆ , Jennifer Lawson _{1,

2} , Jennifer M Rendell ₂ , Hasanen Al-Taiar ₁ , Alison Lennox ₁ , Farooq Ahmad ₃ , John R Geddes _{1,

2}

Affiliation

Current options for treating emergent episodes of hypomania and mania in bipolar disorder are limited. Our objective was to compare the effectiveness and safety of add‐on melatonin in hypomania or mania over 3 weeks as a well‐tolerated therapy.

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