An eight‐week research was conducted to investigate the effects of single or combined administration of sodium propionate (Na‐P) and sodium acetate (Na‐A) on the performance of yellowfin seabream (Acanthopagrus latus) juveniles (6.5 ± 0.3 g). A plant protein (PP)‐rich diet was supplemented with sole or blends of organic acid salts (OAS) namely Na‐P and Na‐A to design six experimental feeds including control (without OAS), Na‐P5 (5 g/kg Na‐P), Na‐P10 (10 g/kg Na‐P), Na‐A5 (5 g/kg Na‐A), Na‐A10 (10 g/kg Na‐A) and Na‐P + A (5 g/kg Na‐P + 5 g/kg Na‐A). Except for Na‐A5 group, the other OAS‐supplemented treatments had higher growth and feed efficiency ratio than the control (p < .05). The inclusion of OAS in the experimental feeds pronouncedly enhanced plasma lysozyme and alternative complement pathway activities compared to the control. Furthermore, fish fed on the OAS‐supplemented diets had greater catalase and glutathione peroxidase activities in the liver than the control (p < .05). Total antioxidant capacity in the liver of fish fed on the OAS‐supplemented diet also was higher than the control. Fish fed on the OAS‐supplemented diets had higher pepsin, trypsin and lipase activities than the control. The insulin‐like growth factor 1 (IGF‐1) gene expression was remarkably down‐regulated in the liver of fish fed on the OAS‐supplemented diets compared to the control especially in groups fed on the Na‐P10 and Na‐A10 diets. The greatest IGF‐1 gene down‐regulation level in the gut was in fish fed on the Na‐P5 and Na‐P10 diets. The interleukine‐1β in the gut was remarkably up‐regulated in the control compared to the other groups (p < .05). The lactic acid bacterial colonies count in the gut of the control was lower than the OAS‐supplemented groups. Based on the findings of the present study, supplementing PP‐rich diets with 10 g/kg Na‐P or blends of Na‐P (5 g/kg) and Na‐A (5 g/kg) beneficially alleviated inflammatory responses and improved immune parameters and digestive capacity in yellowfin seabream juveniles.

中文翻译：

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日粮有机酸盐可减轻植物蛋白诱导的炎症反应，并改善黄鳍鲷（Acanthopagrus latus）的体液免疫，抗氧化状态和消化酶活性。

进行了为期八周的研究，以研究单次或联合施用丙酸钠（Na-P）和乙酸钠（Na-A）对黄鳍鲷（Acanthopagrus latus）幼鱼（6.5±0.3 g）的性能的影响。富含植物蛋白（PP）的饮食中补充了唯一或混合的有机酸盐（OAS）Na‐P和Na‐A，以设计六种实验性饲料，包括对照品（不含OAS），Na‐P5（5 g / kg Na‐P），Na‐P10（10 g / kg Na‐P），Na‐A5（5 g / kg Na‐A），Na‐A10（10 g / kg Na‐A）和Na‐P + A（ 5 g / kg Na‐P + 5 g / kg Na‐A）。除Na-A5组外，其他OAS补充处理的生长和饲料效率比均高于对照组（p <.05）。与对照相比，实验饲料中包含的OAS显着增强了血浆溶菌酶和其他补体途径的活性。此外，以OAS补充饮食喂养的鱼肝脏中的过氧化氢酶和谷胱甘肽过氧化物酶活性高于对照组（p <.05）。用OAS补充饮食喂养的鱼肝中的总抗氧化能力也高于对照。用OAS补充饮食喂养的鱼的胃蛋白酶，胰蛋白酶和脂肪酶活性高于对照组。与对照组相比，以OAS补充饮食喂养的鱼的肝脏中胰岛素样生长因子1（IGF-1）基因表达显着下调，尤其是以Na-P10和Na-A10饮食喂养的组。肠道中最大的IGF-1基因下调水平是在以Na-P5和Na-P10饲料喂养的鱼中。与其他组相比，对照组中肠道中的白细胞介素-1β显着上调（p <.05）。对照组肠道中的乳酸菌菌落计数低于补充OAS的组。根据本研究的发现，在富含PP的饮食中添加10 g / kg Na-P或Na-P（5 g / kg）和Na-A（5 g / kg）的混合物有益于减轻炎症反应并改善黄鳍金枪鱼幼鱼的免疫参数和消化能力。