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Neuroimaging and intervening in memory reconsolidation of human drug addiction
Science China Information Sciences ( IF 8.8 ) Pub Date : 2020-05-29 , DOI: 10.1007/s11432-019-2847-8
Chuan Fan , Yan Cheng , Huixing Gou , Chang Liu , Shengliang Deng , Chialun Liu , Xianwen Chen , Junjie Bu , Xiaochu Zhang

Reconsolidation refers to memory reprocessing when consolidated memory is being recalled and restored. Importantly, as memory is being recalled, it could further modify past memories. Memory reconsolidation has been identified as a critical role in various types of mental disorders, in particular drug addiction. In this review, we first review earlier studies related to reconsolidation. Secondly, we characterize memory reconsolidation processing in human brain via neuroimaging studies. Then we focus on the role of reconsolidation and reconsolidation-based interventions in drug addiction. Finally, we highlight the potentials of combining reconsolidation-based interventions and neuroimaging techniques as a therapeutic tool in drug addiction.



中文翻译:

神经成像和干预人类吸毒成瘾的记忆重建

重新整合是指重新调用和还原整合内存时的内存重新处理。重要的是,当记忆被召回时,它可以进一步修改过去的记忆。记忆再巩固已被确定为各种类型的精神障碍,特别是药物成瘾的关键作用。在本文中,我们首先回顾了与重组有关的早期研究。其次,我们通过神经影像学研究来表征人脑中的记忆重建过程。然后,我们将重点放在重新整合和基于重新整合的干预措施在吸毒成瘾中的作用。最后,我们强调了将基于重组的干预措施和神经影像技术相结合作为药物成瘾的治疗工具的潜力。

更新日期:2020-05-29
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