Background: Synchronous and antisynchronous activity between neural elements at rest reflects the physiological processes underlying complex cognitive ability. Regional and pairwise connectivity investigations suggest that perturbations in these activity patterns may relate to widespread cognitive impairments seen in bipolar disorder (BD). Here we take a network-based perspective to more meaningfully capture interactions among distributed brain regions compared to focal measurements and examine network-cognition relationships across a range of commonly affected cognitive domains in BD in relation to healthy controls.

中文翻译：

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双相情感障碍认知功能的静息状态网络模式：图论分析。

背景：静止时神经元之间的同步和反同步活动反映了复杂认知能力背后的生理过程。区域性和成对连接性调查表明，这些活动模式的扰动可能与双相情感障碍 (BD) 中普遍存在的认知障碍有关。在这里，我们采用基于网络的视角，与焦点测量相比，更有意义地捕捉分布式大脑区域之间的相互作用，并检查与健康对照相关的 BD 中一系列普遍受影响的认知域的网络认知关系。