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Twin Research and Human Genetics ( IF 0.9 ) Pub Date : 2020-05-26 , DOI: 10.1017/thg.2020.33
Jaakko Kaprio 1, 2 , Dorret I Boomsma 3
Affiliation  

Cohort studies are essential for conducting large studies of multiple exposures and outcomes in humans. Recently, the ability to combine data from multiple cohorts in, for example, meta-analyses, and the willingness in the genetics community to collaborate to enable replication studies has led to many new insights into the genetic and environmental determinants of human health and behaviors. The contribution of Professor Nicholas Martin to the development of cohort studies, particularly of twin and twin-family studies, over a period of several decades is reviewed. He has contributed to the development and use of both Australian and international resources. The contributions of Australian twin studies to genomewide association projects are multiple, and across multiple domains, from biomarkers, lifestyle and behavior to disorders and disease.

中文翻译:

队列

队列研究对于进行人类多重暴露和结果的大型研究至关重要。最近,将来自多个队列的数据组合到元分析中的能力,以及遗传学界合作实现复制研究的意愿,导致了对人类健康和行为的遗传和环境决定因素的许多新见解。回顾了几十年来 Nicholas Martin 教授对队列研究,特别是双胞胎和双胞胎家庭研究发展的贡献。他为澳大利亚和国际资源的开发和利用做出了贡献。澳大利亚双胞胎研究对全基因组关联项目的贡献是多方面的,跨越多个领域,从生物标志物、生活方式和行为到疾病和疾病。
更新日期:2020-05-26
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