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Context matters: Situational stress impedes functional reorganization of intrinsic brain connectivity during problem solving
bioRxiv - Neuroscience Pub Date : 2020-05-29 , DOI: 10.1101/2020.05.26.117499
Mengting Liu , Robert A. Backer , Rachel C. Amey , Eric E. Splan , Adam Magerman , Chad E. Forbes

Extensive research has established the relationship between individual differences in brain activity in a resting state and individual differences in behavior. Conversely, when individuals are engaged in various tasks, certain task-evoked reorganization occurs in brain functional connectivity, which consequently can influence individuals' performance as well. Here, we show that resting state and task-dependent state brain patterns interact as a function of contexts engendering stress. Findings revealed that when the resting state connectome was examined during performance, the relationship between connectome strength and performance only remained for participants under stress (who also performed worse than all other groups on the math task), suggesting stress preserved brain patterns indicative of underperformance whereas non-stressed individuals spontaneously transitioned out of brain patterns indicative of underperformance. These findings were subsequentially replicated in an independent sample set. Implications are discussed for network dynamics as a function of context.

中文翻译:

背景很重要:在解决问题期间,情境压力阻碍了内在大脑连通性的功能重组

广泛的研究已经建立了处于静止状态的大脑活动的个体差异与行为的个体差异之间的关系。相反,当个人从事各种任务时,大脑功能连接中会发生某些由任务引起的重组,因此也会影响个人的表现。在这里,我们表明,休息状态和任务依赖状态的大脑模式根据产生压力的环境进行交互。研究结果表明,在表演过程中检查静止状态连接套时,连接套强度与性能之间的关系仅适用于处于压力下的参与者(他们在数学任务上的表现也比所有其他小组都要差),这表明压力保留了表现不佳的大脑模式,而没有压力的人自发地从表现不佳的大脑模式过渡。这些发现随后被复制到一个独立的样本集中。讨论了根据上下文对网络动态的影响。
更新日期:2020-05-29
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