Idiopathic normal pressure hydrocephalus (iNPH)–the leading cause of reversible dementia in aging–affects 5.9% of adults older than 80.¹ The clinical presentation of iNPH combining gait disorders, impaired cognition (ie, poor executive function and memory), and urinary incontinence is unspecific in aging and frequently found in alternate neurological and non-neurological conditions, such as Parkinson disease or vascular dementia, also called iNPH mimics or iNPH mimickers. In the Geneva Normal Pressure Hydrocephalus cohort, we reported a prevalence of 45.6% of iNPH mimics among a cohort of 125 patients with suspicion of iNPH.²

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评论：特发性常压性脑积水患者的其他诊断方法的流行和管理意义。

特发性常压脑积水（iNPH）是衰老中可逆性痴呆的主要原因，影响5.9％的80岁以上成年人。¹ iNPH的临床表现包括步态障碍，认知能力减退（即执行功能和记忆力差）和尿失禁，在衰老过程中没有特异性，并且经常在其他神经系统和非神经系统疾病（例如帕金森病或血管性痴呆）中发现称为iNPH模拟物或iNPH模拟物。在日内瓦常压脑积水队列中，我们报告了在125名疑似iNPH的患者队列中，iNPH模仿的患病率为45.6％。²