Most bottling companies in Ethiopia use polyethylene terephthalate bottles to package. However, less attention is given to toxic chemicals that could migrate from packaging material into the water. This study aims to assess leaching and toxicological conditions in PET bottled water due to prolonged storage and exposure to direct sunlight. Allium cepa test was used to determine mitotic index (MI) and chromosomal aberrations (CAs). One‐way analysis of variance (ANOVA) and Dunnet’s multiple comparison test were used. P < 0.05 considered statistically significant. The higher chromosomal aberrations and the lowest mitotic index were significantly observed at high temperature (35°C) for one month at P < 0.000. The lower mitotic index was correlated with growth cycle disturbance leading to cell growth reduction. Further investigation is recommended to describe the mechanism and rate of migration of chemicals from water samples supplied in PET bottle.

中文翻译：

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可变时间尺度下暴露于太阳辐射和温度下的聚对苯二甲酸乙二醇酯瓶中矿泉水的遗传毒性评估

埃塞俄比亚的大多数装瓶公司都使用聚对苯二甲酸乙二醇酯瓶进行包装。但是，对可能从包装材料迁移到水中的有毒化学物质的关注较少。这项研究的目的是评估由于长时间储存​​和暴露在直射阳光下而导致的PET瓶装水中的浸出和毒理学条件。葱属cepa测试用于确定有丝分裂指数（MI）和染色体畸变（CAs）。使用单向方差分析（ANOVA）和Dunnet的多重比较检验。P  <0.05被认为具有统计学意义。较高的染色体畸变和最低的有丝分裂指数被观察到高温（35°C）在P的一个月 <0.000。较低的有丝分裂指数与导致细胞生长减少的生长周期干扰有关。建议进一步研究以描述从PET瓶中提供的水样中化学物质迁移的机理和速率。