The phytochemical profile and potential biological activities of Plantago anatolica Tutel & R. Mill., a traditional endemic food plant of Eastern Anatolia, Turkey, were studied. The study included analysis of phytochemical and mineral compositions of lyophilized sequential extracts (n-hexane, chloroform, ethyl acetate, acetone, ethanol and water) and traditional preparations (herbal infusion, decoction and cold water extraction) obtained from aerial parts of the P. anatolica plant, followed by evaluation of their antioxidant capacities and inhibitory activities towards enzymes involved in metabolic syndrome. Chromatographic studies showed that phenolic compounds (caffeic and chlorogenic acids, apigenin and kaempferol), and fatty acids (palmitic and linolenic acids) and an aromatic compound benzotiazole were the major phytochemicals. The ethanol extract and the herbal infusion extracted the most caffeic acid. These two preparations showed significant oxygen radical absorbance capacity (1.9 and 1.0 mmol Trolox equivalent/g dw, respectively), high ferric reducing antioxidant power (0.9 and 0.7 mmol Fe²⁺/g dw, respectively), 2,2-diphenyl-1-picrylhydrazyl radical scavenging capacity (IC₅₀: 0.87 and 0.34 mg/ml, respectively), and ferric chelation activities (IC₅₀: 0.09 mg/ml). Both preparations showed high inhibitory activities towards α-glucosidase (IC₅₀ of 0.8 and 0.6 mg/ml, respectively), and lipase (IC₅₀ of 72 and 44 μg/ml, respectively) but low inhibitory activities towards α-amylase (IC₅₀: 4.31 and 5.32 mg/ml, respectively). These results highlighted the potential of P. anatolica as a source of phytochemicals with strong antioxidant and enzyme inhibitory properties for application in the food and biopharmaceutical industries.

研究了土耳其安那托利亚东部传统特有的食用植物-车前草（Plantago anatolica Tutel＆R. Mill。）的植物化学特征和潜在的生物学活性。这项研究包括分析从P的地上部分获得的冻干连续提取物（正己烷，氯仿，乙酸乙酯，丙酮，乙醇和水）和传统制剂（草药注入，汤剂和冷水提取）的植物化学和矿物成分。无花果植物，然后评估其抗氧化能力和对涉及代谢综合征的酶的抑制活性。色谱研究表明，酚类化合物（咖啡酸和绿原酸，芹菜素和山acids酚），脂肪酸（棕榈酸和亚麻酸）和芳香族化合物苯并噻唑是主要的植物化学物质。乙醇提取物和草药浸膏提取的咖啡酸最多。这两种制剂显示出显着的氧自由基吸收能力（分别为1.9和1.0 mmol Trolox当量/ g dw），高铁还原抗氧化剂能力（分别为0.9和0.7 mmol Fe ²⁺ / g dw），2，2-二苯基-1 -piclllhydrazyl自由基清除能力（IC ₅₀：分别为0.87和0.34 mg / ml）和铁螯合活性（IC ₅₀：0.09 mg / ml）。两种制剂表明对α葡萄糖苷酶的高抑制活性（IC ₅₀分别为0.8和0.6毫克/毫升），和脂肪酶（IC ₅₀朝着α淀粉酶，但低的抑制活性的72和44微克/毫升，分别地）（IC ₅₀：分别为4.31和5.32 mg / ml）。这些结果突出了P的潜力。 anatolica作为具有强抗氧化剂和酶抑制特性的植物化学物质的来源，可用于食品和生物制药行业。