Development of membrane-associated molecularly imprinted materials with fast and high permselectivity has been significant needed in separation engineering field. Herein, for the first time, a subversive synthesis strategy with hierarchical structure was proposed for the preparation of nanocomposite blended molecularly imprinted membranes (NBMIMs). Artemisinin, the high-efficiency antimalarial drug, was chosen as the template molecule. Instead of the direct modification of nanocomposite on membrane surfaces, the double-bonded TiO₂@PDA was initially prepared, the blended membrane synthesis procedure was then conducted through a phase conversion process by using the as-prepared TiO₂@PDA and PVDF powder as host materials. Importantly, the double-bonded TiO₂@PDA-based nanocomposite in blended membranes was first proposed and applied as imprinting-initiated factor during the next artemisinin-imprinted process, leading the formation of imitated core-shell structure on membrane surfaces. It was no surprise that more excellent rebinding capacity (66.9 mg g⁻¹), fast adsorption kinetics and high permselectivity coefficients (more than 17) were successfully achieved. Furthermore, an important conclusion was also obtained that TiO₂@PDA-based nanocomposite from NBMIMs would cause significant enhancement of the rebinding capacity, that is to say, more and more artemisinin-imprinted sites would be synthesized by increasing the dosage of TiO₂@PDA until 0.5 g. Therefore, a novel direction for the design and manipulation of MIMs materials had been successfully designed and guided for selective separation of artemisinin.

具有快速和高选择性的膜相关分子印迹材料的开发在分离工程领域中是非常需要的。本文首次提出了一种具有层次结构的颠覆性合成策略，用于制备纳米复合共混分子印迹膜（NBMIMs）。选择高效抗疟药青蒿素作为模板分子。代替直接修饰膜表面上的纳米复合材料，首先制备了双键的TiO ₂ @PDA，然后使用所制备的TiO ₂ @PDA和PVDF粉末，通过相转化工艺进行了共混膜合成程序。主机材料。重要的是，双键TiO ₂首先提出了基于PDA的纳米复合膜，并在下一个青蒿素的印迹过程中将其用作印迹引发因子，从而导致在膜表面形成了模仿的核壳结构。毫不奇怪，成功实现了更出色的再结合能力（66.9 mg g ^-1），快速的吸附动力学和高的选择性渗透系数（超过17）。此外，还获得了重要的结论，即来自NBMIMs的TiO ₂ @PDA基纳米复合材料将显着提高结合能力，也就是说，通过增加TiO ₂的剂量将合成越来越多的青蒿素印迹位点。@PDA直至0.5g。因此，已成功设计并指导了MIMs材料设计和操作的新方向，并为选择性分离青蒿素提供了指导。