Pleural effusion adenosine deaminase (ADA) levels are elevated in various diseases. We investigated whether pleural effusion ADA levels differ among patients with malignant pleural mesothelioma (MPM), lung cancer (LC), and benign diseases, including tuberculous pleurisy. We examined 329 patients from February 2002 to July 2013. There were 131 MPM cases with ADA levels of 32.29 IU/L; 117 LC cases with ADA levels of 21.12 IU/L; 54 benign disease cases with ADA levels of 20.98 IU/L. A significant difference existed in pleural effusion ADA levels between MPM and benign disease patients. Pleural effusion ADA levels were significantly higher in MPM patients.

在各种疾病中胸腔积液腺苷脱氨酶（ADA）的水平升高。我们调查了恶性胸膜间皮瘤（MPM），肺癌（LC）和良性疾病（包括结核性胸膜炎）患者的胸腔积液ADA水平是否存在差异。从2002年2月至2013年7月，我们检查了329例患者。其中131例MPM病例的ADA水平为32.29 IU / L。117例LC病例，ADA水平为21.12 IU / L；54例良性疾病病例的ADA水平为20.98 IU / L。MPM和良性疾病患者的胸腔积液ADA水平存在显着差异。MPM患者的胸腔积液ADA水平显着升高。