当前位置: X-MOL 学术Biotechnol. Biotechnol. Equip. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Noninvasive extendable prosthesis: a new design
Biotechnology & Biotechnological Equipment ( IF 1.4 ) Pub Date : 2020-05-29
Jie Zhang, Zhaohua Chang, Lizheng Zhang, Ping Ye, Tianxi Chi

Abstract

The treatment of choice for distal femur malignancies in skeletally immature patients remains controversial. As the mainstream treatment, limb-salvage treatment has been recently investigated, but its application in children remains challenging. Specifically, the procedure causes potential limb-length discrepancy from the continued normal growth of the contralateral lower extremity. We designed a new type of noninvasive prosthesis that is extendable within the body. To evaluate our prosthesis’ reliability and extensibility, in vitro and in vivo (animal) experiments were conducted. The in vitro experiment was used to verify the lengthening performance of the prosthesis. In the in vivo experiment, to determine the extension length and internal structure condition, the prosthesis was implanted into the rear femoral limb of a sheep under fluoroscopic guidance. Expansion was achieved with the aid of an external electromagnetic field, and the experiments proved the extensibility and noninvasiveness of our prosthesis. However, many problems need to be resolved.



中文翻译:

无创可扩展假体:新设计

摘要

骨骼不成熟患者股骨远端恶性肿瘤的选择治疗仍存在争议。作为主流治疗方法,近来对肢体挽救疗法进行了研究,但其在儿童中的应用仍然具有挑战性。具体来说,该过程可能导致对侧下肢持续正常生长而导致潜在的肢长差异。我们设计了一种可在体内扩展的新型无创假体。为了评估我们的假体的可靠性和可扩展性,进行了体外体内(动物)实验。在体外实验来验证假体的延长性能。在体内为了确定延伸长度和内部结构条件,在荧光镜引导下将假体植入绵羊的股骨后肢。借助于外部电磁场实现了扩展,并且实验证明了我们假体的可扩展性和无创性。但是,许多问题需要解决。

更新日期:2020-05-29
down
wechat
bug