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An automated sensitive approach for measuring whole gut transit time.
Neurogastroenterology & Motility ( IF 3.5 ) Pub Date : 2020-05-29 , DOI: 10.1111/nmo.13894
Keeley L Baker 1, 2 , Michelle Izydorczak 1 , Ruaidhri Jackson 3 , Justus V Verhagen 1, 2
Affiliation  

Commonly used methods to measure whole gut transit time in rodents have yet to combine high sensitivity, objectivity, and automation. We have developed a novel method using oral gavage of non‐toxic fluorescent dye particles and their detection by fluorescence imaging to enable unbiased automated detection of gut transit time simultaneously in 8 cages.

中文翻译:

一种用于测量整个肠道通过时间的自动灵敏方法。

测量啮齿动物整个肠道通过时间的常用方法尚未结合高灵敏度、客观性和自动化。我们开发了一种新方法,使用口服管饲无毒荧光染料颗粒并通过荧光成像对其进行检测,从而能够在 8 个笼子中同时无偏地自动检测肠道通过时间。
更新日期:2020-05-29
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