当前位置: X-MOL 学术Saudi Pharm. J. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Evaluation of heavy metals in cosmetic products and their health risk assessment.
Saudi Pharmaceutical Journal ( IF 4.1 ) Pub Date : 2020-05-29 , DOI: 10.1016/j.jsps.2020.05.006
Hamna Arshad 1 , Moniba Zahid Mehmood 1 , Munir Hussain Shah 2 , Arshad Mehmood Abbasi 1
Affiliation  

Heavy metals’ contamination in cosmetic products is a serious threat. Present study was conducted to evaluate the concentrations of heavy metals (HMs) in various brands of cosmetic products with special emphasis on their health risk assessment. Five heavy metals including Cd, Cr, Fe, Ni and Pb were quantified in different brands of lotions, foundations, whitening creams, lipsticks, hair dyes and sunblock creams using atomic absorption spectrometry. Risk to the consumer’s health was determined using systemic exposure dosage (SED), margin of safety (MoS), hazard quotient (HQ), hazard index (HI) and lifetime cancer risk (LCR).

On comparative basis, different brands of sunblock creams depicted highest concentration of Ni, Pb and Cr (7.99 ± 0.36, 6.37 ± 0.05 and 0.43 ± 0.01 mg/kg, respectively), whereas lipsticks had elevated levels of Fe at 12.0 ± 1.8 mg/kg, and Cd was maximum in lotions (0.26 ± 0.02 mg/kg). Multivariate analysis revealed strong associations among Cr, Ni and Pb, while Cd and Fe showed disparity in distribution and sources of contamination. MoS, HQ and HI values were within the permissible limit apart from for lotions and sunblock creams, while LCR value was higher than the permissible limit in all cosmetic products except lipsticks. Regular use of these products can cause serious threat to human health, particularly skin cancer on long time exposure. Therefore, continuous monitoring of cosmetic products, particularly with reference to HMs adulteration should be adopted to ensure the human safety and security.



中文翻译:

化妆品中重金属的评估及其健康风险评估。

化妆品中重金属的污染是一个严重的威胁。本研究旨在评估各种化妆品品牌中的重金属(HMs)浓度,并特别强调其健康风险评估。使用原子吸收光谱法定量分析了不同品牌的乳液,粉底,美白霜,口红,染发剂和防晒霜中的五种重金属,包括镉,铬,铁,镍和铅。使用全身暴露剂量(SED),安全系数(MoS),危险系数(HQ),危险指数(HI)和终生癌症风险(LCR)确定对消费者健康的风险。

在比较的基础上,不同品牌的防晒霜描绘了最高的镍,铅和铬浓度(分别为7.99±0.36、6.37±0.05和0.43±0.01 mg / kg),而口红中的Fe含量为12.0±1.8 mg / kg。 kg和Cd在洗剂中最大(0.26±0.02 mg / kg)。多变量分析显示,Cr,Ni和Pb之间有很强的联系,而Cd和Fe在分布和污染源方面存在差异。除乳液和防晒霜外,MoS,HQ和HI值均在允许的范围内,而除口红外,所有化妆品中的LCR值均高于允许的范围。定期使用这些产品会严重威胁人类健康,尤其是长时间接触皮肤癌。因此,持续监测化妆品,

更新日期:2020-05-29
down
wechat
bug