OBJECTIVE Asymmetric walking after stroke is common, detrimental, and difficult to treat, but current knowledge of underlying physiological mechanisms is limited. This study investigated electromyographic (EMG) features of temporal gait asymmetry (TGA). METHODS Participants post-stroke with or without TGA and control adults (n = 27, 8, and 9, respectively) performed self-paced overground gait trials. EMG, force plate, and motion capture data were collected. Lower limb muscle activity was compared across groups and sides (more/less affected). RESULTS Significant group by side interaction effects were found: more affected plantarflexor stance activity ended early (p = .0006) and less affected dorsiflexor on/off time was delayed (p < .01) in persons with asymmetry compared to symmetric and normative controls. The TGA group exhibited fewer dorsiflexor bursts during swing (p = .0009). CONCLUSIONS Temporal patterns of muscular activation, particularly about the ankle around the stance-to-swing transition period, are associated with TGA. The results may reflect specific impairments or compensations that affect locomotor coordination. SIGNIFICANCE Neuromuscular underpinnings of spatiotemporal asymmetry have not been previously characterized. These novel findings may inform targeted therapeutic strategies to improve gait quality after stroke.

中文翻译：

---

中风后颞叶步态不对称的下肢肌肉活动

目的 卒中后不对称行走很常见、有害且难以治疗，但目前对潜在生理机制的了解有限。本研究调查了时间步态不对称 (TGA) 的肌电图 (EMG) 特征。方法 有或没有 TGA 的卒中后参与者和对照成人（分别为 n = 27、8 和 9）进行了自定步态地面步态试验。收集了肌电图、测力板和动作捕捉数据。比较各组和各侧的下肢肌肉活动（受影响更多/更少）。结果 发现显着的组间相互作用效应：与对称和规范对照相比，不对称人群中受影响的足底屈肌站立活动提前结束 (p = .0006)，受影响的背屈肌的开启/关闭时间延迟 (p < .01)。TGA 组在摆动过程中表现出较少的背屈肌爆发 (p = .0009)。结论 肌肉激活的时间模式，特别是在从站姿到挥杆过渡时期的踝关节，与 TGA 相关。结果可能反映影响运动协调的特定损伤或补偿。意义 时空不对称的神经肌肉基础先前尚未得到表征。这些新发现可能为有针对性的治疗策略提供信息，以改善中风后的步态质量。意义 时空不对称的神经肌肉基础先前尚未得到表征。这些新发现可能为有针对性的治疗策略提供信息，以改善中风后的步态质量。意义 时空不对称的神经肌肉基础先前尚未得到表征。这些新发现可能为有针对性的治疗策略提供信息，以改善中风后的步态质量。